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2020
2024-05-27
Modern Pathology丨PITX2 as a Sensitive and Specific Marker for Midgut Neuroendocrine Tumors
Neuroendocrine tumors (NETs) often present as metastatic lesions, and immunohistochemical localization of the site of origin is one of the most important tasks in their pathological assessment.
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2024-04-26
AM J SURG PATHOL | GAD2 is a highly specific marker for pancreatic neuroendocrine tumors
Glutamate decarboxylase 2 (GAD2, also known as GAD65) is one of the two glutamate decarboxylases required for converting glutamate to γ-aminobutyric acid (GABA). GABA is the most important inhibitory neurotransmitter in the central nervous system, capable of reducing the excitability of neurons at nerve terminals and synapses.
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2024-04-26
Latest Advances and Diagnostic Challenges in Endometrial Cancer (Part 2)
The depth of myometrial invasion is an independent predictor of lymph node involvement and overall survival in patients with endometrial carcinoma. Staging requires reporting the absence or presence of myometrial invasion (pT1a, none or <50% myometrial invasion; pT1b, ≥50% myometrial invasion).
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