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TLE1 Antibody Reagent
Product Name:
TLE1 Antibody Reagent
Item Number:
CTB268
Specifications
Registration Certificate Name:
TLE1 Antibody Reagent (Immunohistochemistry)
Species:
Rabbit monoclonal antibody
Clone Number:
122006D21
Cell Localization:
Nucleus
Positive Control:
Synovial sarcoma
Repair Method:
Product Specifications:
3/6/12ml
Product Introduction:
TLE1 (Transducin like enhancer of split 1) is located at chromosome 9q21.32 and is a member of the TLE gene family. It is involved in the differentiation of hematopoietic cells, neurons, and terminal epithelium. It is expressed in basal layer cells, adipocytes, peripheral nerve cells, endothelial cells, and mesothelial cells. It is specifically expressed in synovial sarcoma and rarely expressed in schwannoma and pleomorphic sarcoma. TLE1 has higher sensitivity and specificity in synovial sarcoma compared to Bcl-2, EMA, and CK, and can be used as a marker for synovial sarcoma to aid in differential diagnosis from other tumor types.
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